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This leads to local amplifying pathways, such as IFN--driven MHC upregulation on microglia and CCL2-mediated monocyte recruitment, which worsen -synuclein pathology and neuronal vulnerability [95]

Glutathione-s-transferases as determinants of cell survival and death [PMID: 22540427] Laboratory literature summary: Glutathione-s-transferases as determinants of cell survival and death

SC-islets from T1D patients have been generated to study the effects of IFN- , TFN- , and IL-1, which are pro-inflammatory cytokines involved in autoimmune-mediated cell injury in T1D (46, 219)